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Thermo A36742 POROS CaptureSelect

簡(jiǎn)要描述:Thermo A36742 POROS CaptureSelect
貨號(hào): A36742
POROS CaptureSelect AAVX Affinity Resin is engineered to addres

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  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時(shí)間:2025-01-16
  • 訪  問  量:416

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品牌Thermofisher Scientific/賽默飛世爾貨號(hào)A36742
規(guī)格供貨周期一周
主要用途科研單位實(shí)驗(yàn)用應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,食品,化工,生物產(chǎn)業(yè),制藥

Thermo A36742 POROS CaptureSelect

Thermo A36742 POROS CaptureSelect

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Thermo Scientific

POROSCaptureSelectAAVX Affinity Resin

貨號(hào): A36742

POROS CaptureSelect AAVX Affinity Resin is engineered to address the high selectivity and capacity requirements for large-scale downstream purification of a broad range of naturally occurring and synthetic adeno-associated virus (AAV) serotypes used for gene therapy applications. POROS CaptureSelect AAVX resin has demonstrated binding reactivity towards a set of AAV serotypes that includes AAV1 to AAV8, and AAVrh10 as well as synthetic serotypes.

Thermo A36742 POROS™ CaptureSelect™ AAVX Affinity Resin

Features of POROS CaptureSelect AAVX resin include:

One-step AAV purification from crude material with high purity and yield

High specificity and capacity, maximizing yield by significantly reducing process steps

Superior capacity maintained at high flow rates

Excellent scalability and easier handling and packing due to rigid polymeric bead

Non-animal derived

 

POROS CaptureSelect AAVX Affinity Resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step. This resin comes with complete technical and regulatory support.

 

View other viral vector resins and supporting products ?

 

Main characteristics

 

Matrix: cross-linked poly(styrene-divinylbenzene) POROS beads

Average particle size: 50 µm

Ligand: CaptureSelect AAVX affinity ligand

Binding capacity: >1x1013 genome copies/mL of resin

Elution conditions: acidic elution with 0.1 M glycine, pH 3.0

Mechanical resistance: 100 bar (1,450 psi; 10 MPa)

Formulation buffer: 18% (v/v) ethanol

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

貨號(hào) 單位規(guī)格

A36742 250 mL

A36739 10 mL

A36740 25 mL

A36741 50 mL

A36743 1,000 mL

A36744 5,000 mL

A36745 10,000 mL

規(guī)格

配基類型:CaptureSelect AAVX affinity ligand

粒徑:50 μm

數(shù)量:250 mL

產(chǎn)品線:POROS

結(jié)合功能:>1x1013 genome copies/mL of resin

運(yùn)輸條件:Wet Ice

基質(zhì):Cross-linked poly(styrene-divinylbenzene) POROS beads

色譜柱類型:Affinity

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